What is Resveratrol?

Resveratrol is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. Resveratrol has many anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Resveratrol is very well known in Western Europe as it can slow down the aging process. Resveratrol is found in the skin of red grapes and is a constituent of red wine. Resveratrol content sin the plamnts are produced in the plant as a defense against disease and fungus. Since fungal infections are more common in cooler climates, grapes produced in cooler climates tend to have a higher concentration of Resveratrol. Total amount of Resveratrol per serving of wine (a 5-ounce glass) for white wines is found to be between 0.01 to 0.27 mg.

Chemical Constituent of Resveratrol

The chemical constituent of the Resveratrol is something that makes it special. Resveratrol (3,5,4′-trihydroxystilbene) is a polyphenolic phytoalexin. It is a stilbenoid, a derivate of stilbene, and is produced in plants with the help of the enzyme stilbene synthase.

It exists as two geometric isomers: cis (Z) and trans (E), with cis-isomer shown in the top image. The trans form can undergo isomerisation to the cis form when exposed to ultraviolet irradiation. Resveratrol content also stayed stable in the skins of grapes and pomace taken after fermentation and stored for a long period. All that means is that That resveratrol can have two forms of existence according to the subject.

Chemical Action Plan of Resveratrol Content

The mechanisms of resveratrol’s apparent effects on life extension are not fully understood, but they appear to mimic several of the biochemical effects of calori restriction. A new report indicates that resveratrol activates Sirtuin 1 (SIRT1) and PGC-1? and improve functioning of the mitochondria. Other research calls into question the theory connecting resveratrol, SIRT1, and calorie restriction..

Resveratrol content interferes with all three stages of carcinogenesis initiation, promotion and progression. Experiments in cell cultures of varied types and isolated subcellular systems in vitro imply many mechanisms in the pharmacological activity of resveratrol. These mechanisms include modulation of the transcription factor NF-kB inhibition of the cytochrome P450 isoenzyme CYP1A1. Resveratrol content was reported effective against neuronal cell dysfunction and cell death, and in theory could help against diseases such as Huntington’s disease and Alzheimer’s disease. Again, this has not yet been tested in humans for any disease.

Owing to all these advantages there are many companies which offer a free trial of this amazing natural supplement.

marryjones777
http://www.articlesbase.com/health-articles/resveratrol-content-943484.html

It is an unavoidable truth that we will all start to grow old and with old age we will all suffer the effects to some degree. One of these effects comes in the form of wrinkles. Basically aging is the process in which our bodies start to deteriorate. It means our metabolic processes and physiological functions start to slow down. However there are now a number of anti aging products on the market that claim to be able to slow down the process of aging by helping to stop the deterioration of our bodies and the onset of wrinkles, one of these products is known as resveratrol.

There has been and continues to be a lot of research carried out revolving around resveratrol, which demonstrates that it could actually be one of the most powerful antioxidants that has ever been found. So what makes this product so good? Well lets start with where it comes from. It originates from several different types of plants including the Japanese knotweed. On top of this it is also found within a number of foods such as peanuts, blueberries, lingon berries, sparkleberries, cranberries, deer berries, partridge-berries, and bilberries. However out of all the places it is found it is the most present within the skin of grapes that go on to be used to make red wine.

When red wine is produced it is said that resveratrol is plentiful within it; however there are now also a lot of resveratrol supplements on the market that contain a very high concentration of resveratrol, higher than what is found within red wine. Basically in order for you to receive the same amount of it that you would get in supplement form it would require you to drink 1,000 bottles of wine a day, something that is pretty much impossible and should never be attempted.

One of the main reasons as to why resveratrol is considered to be so effective when it comes to slowing the aging process is due to the amount of antioxidants that are present within it. This is because they are needed at a high level in order to ensure complete health and as a means of preventing disease. The antioxidants that are present within this substance prevents and repairs cell damage that is caused by free radicals in the body. It is these free radicals that wreak havoc within our bodies due to the fact they damage cells, which not only causes disease but also aging.

Since its discovery and link to antioxidants there have been a lot of research conducted on resveratrol and its effect on aging. The research that has been conducted suggests that it is a powerful antioxidant, which helps to ease the damaging effects of free radicals in the body especially when it comes to the aging process. Also for several years now studies have continued to be carried out that demonstrate conclusively that resveratrol can slow down the aging process.

As I have previously mentioned there are a number of sources of resveratrol so whatever choice you make, whether its to take supplements or to drink red wine just make sure you do it in moderation otherwise you may end up causing more harm than good.

Michael Jenkins
http://www.articlesbase.com/supplements-and-vitamins-articles/anti-ageing-breakthrough-how-resveratrol-antioxidants-slow-the-aging-process-954477.html

Welcome to the most recent, but certainly not the last, fountain of youth. Resveratrol.

Unless you make it a practice to live under a rock, avoid the news, Oprah Winfrey, Dr Oz, 60 Minutes or any specials with Barbra Walters, you have heard, by now, about resveratrol.

Eighteen years ago 60 minutes took their first look at something called the French paradox, which was the appearance that the French had lower instances of heart disease than Americans, despite a lifestyle involving a high fat diet and large amounts of red wine consumption.

Today, researchers have identified a specific substance in the red wine, a fungus to be precise, that they believe, when taken in very high concentrations, may extend life an extra ten to twenty years. That fungus is known by Sirtris as SRT501, and to the rest of us as resveratrol.

Sirtris is the company that 60 Minutes interviewed and depending on your beliefs about huge multi billion dollar companies looking out for the best interests of the consumer, sold themselves to Glaxosmithkline for about 720 million dollars.

This brings me to the number four (Were counting down) bad thing about resveratrol that you should know: The company that owns the research rights and development of resveratrol is the second largest Pharmaceutical company on the planet. Earning over seven billion dollars in revenue last year and established in over 70 countries, this is what is commonly referred to as a Monopoly. Just something to consider when the price to extend your life could arguably become controlled.

Tying in closely to number four is the number three bad thing about resveratrol that you should know: Neither Sirtris, nor glaxosmithkline have their name on any resveratrol product on the market. Thats right. If 60 minutes went strait to the source to bring us the facts about this new wonder pill, why cant we find a bottle anywhere with their name on it being sold? Better yet, Who is making the stuff on the market currently and how good is it?

That brings us to the number two bad thing about resveratrol that you should know: Resveratrol is an herbal supplement that is NOT regulated by the food and drug administration. Thats right. With all the coverage of how great resveratrol is, anyone with Japanese knotweed or a grape vine in their back yard can dry out and grind up product thought to have the active fungus and cram it into a capsule and sell it to you for whatever price they wish to charge with absolutely zero accountability as to its effectiveness.

That brings us to the NUMBER ONE bad thing you should know about resveratrol.

The number one thing you should know about resveratrol is that absolutely no studies exist supporting resveratrol extending the life of humans. That is a fact.

Research Sirtris, research the sirtuin gene, research Christopher Westphal or David Sinclair, a biochemist at Harvard studying the genetic components of aging. Even research centenarian populations in Japan and around the world and the results are always the same. Resveratrol has been proven to extend the life span in yeast perhaps, but not humans. No way, no how, forget it. No proof whatsoever.

In conclusion, should you buy resveratrol for yourself? Thats entirely up to you. The most important thing being emphasized here is just make sure you know the facts and you go in with your eyes open before shelling out hard earned cash under false presumptions.

James
http://www.articlesbase.com/anti-aging-articles/four-bad-things-about-resveratrol-that-you-should-know-957460.html